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  • Anti-PTEN Polyclonal Antibody
產品名稱：

Anti-PTEN Polyclonal Antibody
產品品牌： SOLARBIO/索萊寶 價格：
廠商性質： 生產廠家 產品時間： 2022-08-15
Anti-PTEN Polyclonal Antibody
應用 WB
稀釋比例WB 1:3000.
交叉反應Human Mouse Rat

產品概述

品牌SOLARBIO/索萊寶貨號K106537P
規(guī)格50ul /100ul供貨周期現(xiàn)貨
主要用途WB應用領域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產業(yè),農林牧漁

Anti-PTEN Polyclonal Antibody

英文名稱Anti-PTEN Polyclonal Antibody
宿主Rabbit
別名10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;PTENbeta;TEP1
應用WB
稀釋比例WB 1:3000.
交叉反應Human Mouse Rat
蛋白分子量47kDa
Gene ID5728
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human PTEN
性狀液體
Public Immunogen RangeA synthetic peptide of human PTEN
Subcellular LocationsCytoplasm Nucleus PML body Secreted
Swiss ProtP60484
克隆類型Polyclonal Antibody
背景資料This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

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